Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
Most Useful Reviews
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
Read More
9
Hypertension relief
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
Read More
9
Headache reduction
14 people found this helpful
My migraine occurrences have decreased remarkably, and I enjoy a newfound ease in my life! I've faced occasional constipation; I'm curious if this is related to magnesium intake. Overall, I'm pleased with the improvements.
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
User Reviews
USERS' SCORE
Good
Based on 22 Reviews
8.2
All Reviews
Positive Reviews
Negative Reviews
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
Read More
9
Hypertension relief
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
Read More
9
Headache reduction
14 people found this helpful
My migraine occurrences have decreased remarkably, and I enjoy a newfound ease in my life! I've faced occasional constipation; I'm curious if this is related to magnesium intake. Overall, I'm pleased with the improvements.
Read More
7.5
Mood improvement
14 people found this helpful
After using Doctor's Best 100% High Absorption Magnesium for over 30 days, I've noticed significant improvements in brain function, mood, and stress levels. Within two weeks, my mood improved, and my irritability decreased. This product has been very beneficial for me, and I hope this review helps others.
Read More
9
Migraine relief
3 people found this helpful
Good product for migraines. 80% of migraine sufferers are magnesium deficient, and after suffering migraines for 30 years, I've finally found a solution. I can now take two magnesium pills daily without pain! Menstrual migraines affect many women, leading to heightened headache frequency. Magnesium plays a crucial role in alleviating these symptoms by supporting nerve conduction. I've experienced a significant reduction in migraine severity since starting this supplement during times of stress, and I believe magnesium is vital for overall brain health.
A brain tumor is an abnormal growth of cells in the brain or central spinal canal. These tumors can be classified as either benign (non-cancerous) or malignant (cancerous), and they can originate from the brain tissue itself (primary brain tumors) or spread to the brain from other parts of the body (secondary or metastatic brain tumors). Symptoms may vary widely depending on the tumor's location, size, and type, but common indicators include headaches, seizures, cognitive or behavioral changes, and motor skill deficiencies. Diagnosing a brain tumor typically involves imaging tests such as MRI or CT scans, followed by a biopsy to determine the type of tumor.
Treatment for brain tumors depends on several factors, including the tumor type, size, and location, as well as the patient's overall health. Common treatment options include surgery to remove the tumor, radiation therapy, and chemotherapy. While advancements in medical technology have improved treatment outcomes significantly—enabling more precise targeting of tumors and minimizing damage to surrounding healthy brain tissue—challenges still exist. It's crucial for patients to discuss all available options with their healthcare providers to determine the best course of action tailored to their specific situation.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Based on user reviews, the timeline for seeing results from magnesium supplements can vary significantly. Some users report noticeable benefits within just a couple of weeks. For instance, one review highlights improvements in mood and reduced irritability after only two weeks of usage with Doctor's Best 100% High Absorption Magnesium Read Review. Another user noted that they experienced increased brain function and sleep quality improvements after several days Read Review.
However, long-term users also share their experiences, indicating that substantial benefits, especially related to specific health conditions like brain tumors, may take months or even over a year of consistent use. A user mentioned observing a slight reduction in the size of their benign brain tumor after a year of magnesium supplementation Read Review. This suggests that while some users may notice quick improvements, more significant changes, particularly for serious health issues, might require a longer duration of use.
The available scientific research regarding magnesium supplementation in the context of brain tumors presents a mixed picture. One study explored how magnesium sulfate (MgSO4) impacts patients undergoing surgery for brain tumors and found that it reduced specific protein levels related to brain injury, although it did not markedly alter overall functional outcomes for patients [3]. Another investigation indicated that low magnesium levels might exacerbate neurological symptoms in cancer patients undergoing treatment, suggesting that monitoring and correcting low magnesium could be important in cancer care [2].
Additionally, research on magnesium sulfide nanoparticles demonstrated their potential to significantly reduce the viability of neuroblastoma cells, a type of brain tumor. This suggests that nanoparticles could be a promising avenue for treating this cancer, though further investigation is necessary to understand their full implications [1]. Overall, while there are encouraging findings regarding magnesium’s role in brain tumor management, more extensive clinical studies are needed to establish its efficacy and safety definitively.
Based on user reviews, many individuals have reported significant improvements in various symptoms after incorporating magnesium supplements into their routines. Sleep quality appears to be a common area of benefit, with one reviewer noting a shift from sleepless nights until 3-4 am to a more restful sleep around midnight, expressing immense gratitude for the change Read Review. Additionally, users experiencing migraines have reported a notable reduction in frequency and severity, with one longtime sufferer indicating her migraines have diminished greatly thanks to magnesium supplementation Read Review.
Moreover, users with hypertension and related symptoms have shared their positive outcomes; one user successfully ceased medication after resolving palpitations associated with their magnesium deficiency Read Review. Enhanced cognitive function, mood stabilization, and relief from anxiety have been highlighted by those taking magnesium supplements, underscoring its benefits for mental health. Despite these favorable experiences, it's important to note that individual results can vary, and what works well for one person may not yield the same effects for another.
Based on user reviews, many individuals have reported positive experiences when combining magnesium supplements with other dietary approaches to manage symptoms related to brain tumors. One user mentioned using magnesium supplementation as part of a broader regimen that includes a balanced diet, which resulted in significant improvements in sleep and overall health, particularly for their mother, who was dealing with brain tumor-related stress and headaches Read Review. Furthermore, another person noted that their magnesium use, particularly magnesium threonate alongside other forms, has effectively reduced muscle convulsions and enhanced cognitive function, supporting their overall mental well-being Read Review.
Users also underscore the importance of experimenting with different magnesium types to find the most beneficial combination. One reviewer highlighted magnesium glycinate as helpful for sleep enhancement when taken with magnesium threonate for cognitive support, demonstrating the potential benefits of combining various forms of magnesium in a supplementation strategy Read Review. Overall, combining magnesium with other health-focused practices seems to contribute positively to managing the challenges associated with brain tumors, although individual experiences may vary significantly.
Based on user reviews, many individuals interested in magnesium supplementation for treating brain tumors have shared their positive experiences regarding specific dosage recommendations. One user reports taking magnesium as recommended by their doctor for a calcified benign brain tumor, noting a slight decrease in tumor size after a year of use, which suggests that consistent dosing may play a crucial role in the effectiveness of magnesium in such cases Read Review. Additionally, another user indicated that balancing magnesium dosage with diet led to significant improvements in sleep and overall health, suggesting a holistic approach to treatment alongside magnesium supplementation Read Review.
Overall, while specific dosages were not universally specified, the consensus from user experiences indicates that proper magnesium intake can contribute positively to brain health. Users have highlighted the importance of choosing the right form of magnesium, with mentions of magnesium glycinate and threonate for their beneficial effects on sleep and cognitive function Read Review. However, some users also mentioned gastrointestinal tolerability issues, implying that individuals may need to experiment to find the most effective form and dose that works for their specific needs Read Review.
7.5
Mood improvement
14 people found this helpful
After using Doctor's Best 100% High Absorption Magnesium for over 30 days, I've noticed significant improvements in brain function, mood, and stress levels. Within two weeks, my mood improved, and my irritability decreased. This product has been very beneficial for me, and I hope this review helps others.
9
Enhances cognition
2 people found this helpful
Highly absorbable magnesium is essential for brain function. I truly appreciate L-treonate; I felt its effects just days after starting it. My thoughts have become brisk, rapid, and productive.
7.5
Reduces tumour size
1 people found this helpful
I'm taking this magnesium supplement as recommended by Dr. Fujikawa for my calcified benign brain tumor. After a year of use, I observed that the tumour has slightly decreased in size, prompting me to continue its use.
9
Life-changing effect
106 people found this helpful
Highly recommended! At just 26, I've had sleep issues for years, often not sleeping until 3-4am. After starting DOCTOR’s magnesium pill, I felt relaxed and experienced improved sleep quality. I now sleep around 12-1am, which is a remarkable change! Despite the larger pill size, it wasn’t a concern for me. I’m grateful for including magnesium in my regimen.
9
Headache reduction
14 people found this helpful
My migraine occurrences have decreased remarkably, and I enjoy a newfound ease in my life! I've faced occasional constipation; I'm curious if this is related to magnesium intake. Overall, I'm pleased with the improvements.
9
Hypertension relief
52 people found this helpful
After a year of use, my hypertension and related palpitations have disappeared, allowing me to stop medication. Magnesium deficiency seemed to be the cause of my hypertension, and I feel much better since taking this.
6
Improved sleep quality
I am satisfied: My mother and I experienced frequent headaches, particularly my mother, who suffers from brain tumour-related stress and blood pressure issues. I prefer not to take Tylenol but find magnesium works better for us both. With the right diet, I have noticed significant improvements in my mother's sleep and overall health, leading to a reduction in headaches. Eating a balanced diet has allowed my mother to sleep better, which is a wonderful outcome.
6
Cognitive boost
1 people found this helpful
After experimenting with various magnesium forms over nine months, I found magnesium glycinate particularly helpful for sleep enhancement. I take it roughly 1.5 hours before bed, along with magnesium threonate for cognition, which has significantly reduced muscle convulsions and improved control during activities. I hope others with ADHD see similar benefits from focusing on nutrition.
2
Induces insomnia
Magnesium glycinate is meant to aid sleep, but it makes my brain buzz and causes insomnia, likely due to excess glutamate. I find other magnesium forms like malate more tolerable.
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
References
Nalci OB, Nadaroglu H, Genc S, Hacimuftuoglu A, Alayli A. The effects of MgS nanoparticles-Cisplatin-bio-conjugate on SH-SY5Y neuroblastoma cell line. Mol Biol Rep. 2020;47:9715. doi:10.1007/s11033-020-05987-2
Zappia F, Verzicco I, Simoni R, Ferrari M, Coghi P, et al. Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment. Acta Biomed. 2020;91:365. doi:10.23750/abm.v91i2.8685
Mirrahimi B, Mortazavi A, Nouri M, Ketabchi E, Amirjamshidi A, et al. Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial. Acta Neurochir (Wien). 2015;157:985. doi:10.1007/s00701-015-2376-x